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EXTRACELLULAR VESICLE-INSPIRED THERAPY

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Functional siRNA Delivery by
Extracellular Vesicle-Liposome Hybrid Nanoparticles

METHOD

INFLUENCE OF SHORT TERM STORAGE CONDITIONS
CONCENTRATION METHODS AND EXCIPIENTS ON EXTRACELLULAR VESICLE RECOVERY AND FUNCTION

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EVALUATION AND MANIPULATION OF TISSUE AND CELLULAR DISTRIBUTION

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TOP-EVs
Technology of Protein delivery through Extracellular Vesicles is a versatile platform for intracellular protein delivery

Extracellulaire blaasjes
Voorbij de hype (beyond the hype)

EXTRACELLULAR VESICLE-INSPIRED CARDIAC REPAIR (EVICARE)

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EXTRACELLULAR VESICLES PRODUCTION

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TECHNOLOGY OF PROTEIN DELIVERY VIA EXTRACELLULAR VESICLES (TOP-EVS)

HIGHLIGHTS

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"Vesicles of stem cells have properties of their own that repair damage to the heart. We want to add therapeutic RNA molecules."

Dr. Pieter Vader

"We will try to
develop a new treatment for hypercholesterolemia by permanently removing PCSK9 from hepatocytes
by using cell-derived vesicles."

Dr. Zhiyong Lei

"While CPC-EVs hold great potential to serve as cell-free therapeutic for cardiac repair, more effort must be put in understanding EVs’ mechanism of action and increasing standardization of EV production processes in order to allow for further employment of EV-based therapeutics."

Dr. Emma Mol

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